Detalhe da pesquisa
1.
Improved reference genome of Aedes aegypti informs arbovirus vector control.
Nature
; 563(7732): 501-507, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30429615
2.
Turning a Drug Target into a Drug Candidate: A New Paradigm for Neurological Drug Discovery?
Bioessays
; 42(9): e2000011, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32776366
3.
A novel Caenorhabditis elegans allele, smn-1(cb131), mimicking a mild form of spinal muscular atrophy, provides a convenient drug screening platform highlighting new and pre-approved compounds.
Hum Mol Genet
; 20(2): 245-60, 2011 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20962036
4.
A Cys-loop mutation in the Caenorhabditis elegans nicotinic receptor subunit UNC-63 impairs but does not abolish channel function.
J Biol Chem
; 286(4): 2550-8, 2011 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20966081
5.
Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.
Pharmacol Rev
; 61(1): 39-61, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19293145
6.
Automated phenotyping of mosquito larvae enables high-throughput screening for novel larvicides and offers potential for smartphone-based detection of larval insecticide resistance.
PLoS Negl Trop Dis
; 15(6): e0008639, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34081710
7.
Splice-variant- and stage-specific RNA editing of the Drosophila GABA receptor modulates agonist potency.
J Neurosci
; 29(13): 4287-92, 2009 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19339622
8.
Fast, automated measurement of nematode swimming (thrashing) without morphometry.
BMC Neurosci
; 10: 84, 2009 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19619274
9.
Calcium signalling in mammalian cell lines expressing wild type and mutant human α1-Antitrypsin.
Sci Rep
; 9(1): 17293, 2019 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31754242
10.
Action potential shape change in an electrically coupled network during propagation: a computer simulation.
Invert Neurosci
; 8(2): 83-9, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18481128
11.
Strategies for automated analysis of C. elegans locomotion.
Invert Neurosci
; 8(3): 121-31, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18688666
12.
Chemistry-to-gene screens in Caenorhabditis elegans.
Nat Rev Drug Discov
; 4(4): 321-30, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15803195
13.
Insect toxins - selective pharmacological tools and drug/chemical leads.
Curr Opin Insect Sci
; 30: 93-98, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30553492
14.
The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease.
Int J Parasitol Drugs Drug Resist
; 8(2): 350-360, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29957333
15.
An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes.
Int J Parasitol Drugs Drug Resist
; 8(1): 8-21, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29223747
16.
The Abeta1-42M35C mutated amyloid peptide Abeta1-42 and the 25-35 fragment fail to mimic the subtype-specificity of actions on recombinant human nicotinic acetylcholine receptors (alpha7, alpha4beta2, alpha3beta4).
Neurosci Lett
; 427(1): 28-33, 2007 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-17945421
17.
Actions of snake neurotoxins on an insect nicotinic cholinergic synapse.
Invert Neurosci
; 7(3): 173-8, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17710455
18.
Mechanisms of Action, Resistance and Toxicity of Insecticides Targeting GABA Receptors.
Curr Med Chem
; 24(27): 2935-2945, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28606041
19.
Modes of Action, Resistance and Toxicity of Insecticides Targeting Nicotinic Acetylcholine Receptors.
Curr Med Chem
; 24(27): 2925-2934, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28176635
20.
Structure and function of two-pore-domain K+ channels: contributions from genetic model organisms.
Trends Pharmacol Sci
; 26(7): 361-7, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15939489